On the Privileges and Other Settings screen, you can configure the agent self-protection feature to prevent other programs and even the user from modifying or deleting files that the Security Agent uses.
When you enable Protect files used by the agent and the Security Agent is running on an endpoint, Apex One (Mac) locks the following files and folders:
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/Library/Application Support/TrendMicro/RPD
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/Users/*/Library/Application Support/TrendMicro/dlpmac.app
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/Library/LaunchDaemons/com.trendmicro.tmes.plugin.plist
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/Library/LaunchDaemons/com.trendmicro.tmsm.rpd.plist
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/Users/*/Library/Application Support/TrendMicro/chromeNativeDLP
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/Users/*/Library/Application Support/TrendMicro/firefoxNativeDLP
Apex One (Mac) allows files to be added in the /Library/Application Support/TrendMicro/Tools folder, files cannot be deleted from the folder.