Trend Micro
Apex Central consolidates your
               organization's suspicious object information and synchronizes the suspicious objects
               among
               integrated managed products. After Trend Micro Email
                  Security is registered to
               Apex Central, Apex Central automatically synchronizes
               the suspicious URLs, file SHA-1 hashes, and file SHA-256 hashes with Trend Micro Email
                  Security at a scheduled time interval. In addition to its own
               scanning mechanism, Trend Micro Email
                  Security cancan leverage the suspicious
               objects to detect known or potentially malicious files and URLs during scanning. 
For more information about how Apex Central manages suspicious object lists, see the Apex Central Administrator's Guide.
		